Wednesday , February 8 2023

Cholesterol-lowering drugs may weaken the nervous system



Cholesterol-lowering medication muscles can weaken the nervous system (represented image) & nbspPhoto Credit: & nbspThinkstock

Washington DC: Drugs that are assigned to people with high levels of cholesterol may be able to weaken the patient's muscles and nervous system, and a work has been done. According to a study published in the journal Cell Metabolism, it reduces the formation of brown fatty tissue that helps transform the statin into sugary and fatty heat. People with brown adipose tissue are better in winter controlling body temperature and are less likely to experience weight or diabetes.

A group of researchers looked at the question that white fatty cells that form the fat layer underneath our skin turn into good brown fat cells. Cell culture studies have found that the biochemical pathway responsible for the production of cholesterol plays a key role in this change. They also found that the main molecule that regulates the transformation is metabolite geranilgeranil pyrophosphate.

8,500 patients examined positron emission tomography scans. Determine if this person has brown oil tissue. It has also been known that patients have taken statins. Scales assessment shows that 6% of those who do not take the drug have brown oil tissue, but this type of tissue is available in only a fraction of only those who receive statins.

Researchers have conducted a separate clinical trial of 16 people to show that statins reduce the brown fatty tissue activity. "We need to think that statins are extremely important to prevent cardiovascular disease, saving millions of people around the world and setting up for a very good reason," said Christian Wolfrum, a researcher.

However, statins also have a negative effect: high doses increase the risk of diabetes mellitus – as shown in other studies.

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