Monday , January 30 2023

Why Flames Can Have The Secret To Fighting Influenza – BBC News


American scientists have recruited a strange ally in their efforts to develop a cure for the flu: the flame.

The blood of this animal South America has become accustomed produce a new antibody therapy that they have the potential fight against all types of flu, including pandemics.

The flu is one of the most subtle diseases when it comes to changing form, and constantly changes his appearance to avoid our immune system, which explains why vaccines are not always effective and every winter we need a new injection to prevent it.

That's why science is chasing a way to end all types of flu, regardless of what the strain comes from or how much it changes.

Y awhere the flame enters, better known for his wool.

Woman is vaccinated against H1N1 flu
Influenza vaccines are not always effective.

These animals, typically the Andes, produce incredibly small antibodies compared to ours.

Antibodies are the weapons of the immune system and are linked to the proteins that protrude from the surface of the virus.

Human antibodies tend to attack the advice of these proteins, but that's where the flu changes more quickly.

While flame antibodies use their advantageous size to snore deeper and attack parts where flu can not change.

Synthetic antibodies

A team at the Scripps Institute in California infects flames with multiple types of flu to cause an immune response.

They then investigated the blood of these auquénidos in search of him more potent antibodies which could attack a wide variety of influenza strains.

The flu virus
Influenza virus is able to rapidly change the edges of proteins protruding from it.

The scientists eventually chose four and then began to develop their own own synthetic antibody who used data from each.

The result was examined in mice receiving lethal doses of influenza.

"It is very effective, it has been 60 different types of viruses which was used in the challenge and only one was not neutralized and it is a virus that does not affect humans, "said one of the researchers, Professor Ian Wilson, in the BBC Science in Action program.

"The goal here is to provide something that works from station to station and it also protects you from possible pandemics if they occur," the scientist explains.

The papers were published in the journal Science and is still in a very early phase and the team wants perform more tests before you start testing with people.

The Holy Grail

Investigators they used two different techniques his time administration of antibodies in animals.

The first was their infusion and the second one into a gene therapy.

Lama to the Andes
Llamas are one of the four types of camelids or camelids in South America.

The genetic guidelines for antibody development were packaged in an innocuous virus, which was then used to infect the mice of the mice.

And the cells in the lining of the nose began to produce the anti-influenza antibody.

A further advantage of this is that It could work for the elderly.

The greater the immune system, the less the seasonal influenza vaccine becomes less effective.

but this Flame therapy does not need to train our immune system.

Professor Jonathan Ball, of the University of Nottingham, told BBC: "The treatment that can work on a variety of different strains of the virus is very desirable. Holy Grail of Influenza"

"There will be appetite (for healing), but it will depend on how well it works, how expensive it will be," he said.


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