Friday , March 31 2023

Hebrew University researchers develop technology to print 3-D drugs – News Israel


Researchers at the Hebrew University's Three-Dimensional and Operational Printing Center

Researchers at the Hebrew University's Three-Dimensional and Operational Printing Center.
(credit photo: courtesy)


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Researchers from the Jewish University of Jerusalem on Wednesday presented their new technology for three-dimensional drug capsule printing, allowing customization and personalization of drugs not available with conventional manufacturing techniques.

Professor Shlomo Magdassi, head of the University's higher education and functional printing center, Ofra Benny, a researcher at the University's Institute for Drug Research, presented their state-of-the-art technology at the second annual 3-D Printing and Beyond conference in Jerusalem, which attracted 3-D printing experts from a number of global industries.

The new technology allows printing of customized drugs from hydrogel objects, producing complicated structures that can be expanded, reshaped, and turned on in a delayed program. By formulating customized drugs, doctors will be able to accurately adjust exposure and dosage levels for individual patients.

"We now have the technology to replace standard or traditional compositions. The population is aging, so we need to think about solutions," Benny said.

"We can now think of combining drugs together in a drug instead of ten, adjusting drug kinetics and improving patient compliance in drug management."

By precisely adjusting the geometry, surface and index of the tablet's swelling by means of 3-D printing, the concept of group concept demonstrates improved targeting of the drug release site in the digestive tract as well as greater control of drug release timing and duration .

"Technology is progressing, it's not a big dream to see mass production in the near future," Benny added.

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"Prof. Magdassi and Dr. Benny's research is an excellent example of such interdisciplinary transformative inventions coming from the Jewish University," said Dr. Yaron Daniely, Managing Director and President of Yissum, the technology transfer company of the university.

"This technology brings us closer to a future in which the medical sector can offer personalized patient care," said Daniely.

The annual conference attracts industry leaders and researchers from areas with growing interest in the potential of 3-D printing, including pharmaceuticals, electronics, defense, automotive and even "processed" food.

"The field of 3-D printing is really rising all over the world," said Magdassi The Publishing of Jerusalem. He co-organized the conference, funded by the Jerusalem Development Authority, Yissum and the Jewish University.

"Israel is the capital of the 3-D printing industry, with many start-up companies and established companies here." Speakers coming from abroad show the importance of this field for the world. 3-D printing in Israel, open to all academic institutions and companies. "

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