Thursday , June 8 2023

Supplement Experts: Do not throw money into this feature Health


Fish oil, vitamin D, new drugs and new cholesterol guidelines – news from a conference of the American Heart Association (AHA) and the American College of Cardiology for research combining what prevents heart attack and other problems.

As announced this week, the good news from the conference for all is that, at least in the United States, you do not have to die before blood testing to control cholesterol – it's ok for most people to let something eat before you get blood for analysis.

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Nutritional supplements in tablets and capsules – 'dietary supplements' are largely lost, 'they do not waste money that way' – doctors concluded that as a basis of health they suggest natural food and a balanced diet and only if this is not enough, adding vitamins or metal tablets, but not with their hands, but only with the physician's recommendation, individually, only for the patient in need.

They also explained that "supplements are, as their name implies, complementary and not substitutes for vitamins and minerals in foods that are the best health base," said Penny Kris-Eterton, MD, PhD, researcher, professor State Pennsylvania College.

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Thus, for example, doctors at the conference once again confirmed that instead of vitamin D as "supplements," it is necessary to eat twice as much fat as a fish or at least to get fish oil better suited to research among cardiac patients than the "supplements".

These and other conclusions adopted at the conference were attended by authors – doctors, none of whom are financially affiliated with drug manufacturers, according to AP.

Two major studies presented at the conference gave mixed results for fish oil or omega-3 fatty acids. There are also several types, including EPA and DHA.

In a study of 26,000 healthy people, one gram per day of the EPA / DHA combination, the dose and the formulations in many supplements – "supplements" – did not show a clear chance of reducing the risk of heart problems or cancer problems.

But another study, which examined four grams of concentrated EPA per day, found that it reduces the heart problems of people at higher risk due to high triglycerides – a type of fat in the blood.

The first study on the impact of a smaller amount of fish oil on the general population included the effect of vitamin D, one of the most popular "supplements", and found it did not reduce the risk of cancer or heart problems.

"We have to accept that this test was good," and that vitamin D as "supplements" has no value attributed to it, said Dr Jane Armitage of Oxford University, United Kingdom. "We see no benefit from him."

"Do not throw money on these additives" that are not well-tuned and of a different quality, said Dr. Dipak Bat from Boston Botanical Hospital.

All of this is reported in the instructions of the Heart Association and the American College of Cardiology, which have been approved by other groups of doctors.

In a multidisciplinary conference on heart disease, the leading cause of death worldwide, new guidelines for cholesterol levels lead to arterial lesions that lead to heart or stroke.

Five years ago, when the guidelines for determining cholesterol lowering therapy were last revised, it surpassed the simple use of a single number in cholesterol levels to determine who needs treatment. It started with a formula that, in order to broaden the risk assessment, takes into account age, high blood pressure and other factors.

This was confusing for doctors, so that the new guidelines introduced at last week's conference brought together both approaches, setting formula goals and taking into account the personal "personal circumstances" of each patient, such as other health conditions or family history of early heart disease.

"It will never be simple enough – a measure of cholesterol," as this does not give a clear picture of the risk, said Dr. Donald Lloyd-Johnson of the University of Northwestern.

If treatment is required, a doctor's first choice remains "statin" which is sold as a cheap generic medicine. For people at high risk, such as those who have already suffered a heart attack, the guidelines suggest adding another generic medicine, also a cheap "ezetimibe" if "statin" does not reduce cholesterol enough. Only if the two drugs do not help enough, strong but expensive new drugs, called "PCSK9 inhibitors", should be considered.

Finally, according to the guidelines, although after all the analyzes it is not clear if necessary treatment is needed, a calcium test in the coronary artery, which is a type of radiation examination with a dose of radiation similar to mammography, should be performed, but some participants in the conference consider this method very expensive because the review costs $ 100 to $ 300.

A conference of the American Heart Association confirmed the finding that a relatively new drug, approved this year, helped not only people with diabetes to control blood sugar but also reduce the risk of hospitalization due to heart failure. Cases are followed by diabetes.

As people with diabetes suffer from heart disease, new diabetes drugs should be tested in large studies to show that they are not dangerous to the heart.

Such a general emphilliflozine drug surprised doctors several years ago by reducing the risk of heart failure and stroke, but another, generic kanagliflozin later had side effects.

The new study looked at the third drug, general daplegiflozine, in over 17,000 diabetic patients with other cardiac risk factors and lower rates of hospitalization due to heart failure, was reported this week in the United States after a conference of the American Heart Association and the American College of Cardiology .

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